糖鎖利用による革新的創薬技術開発
分担研究者:東北大学 加藤幸成
2016年度〜2020年度


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東北大学大学院医学系研究科 抗体創薬研究分野
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*本プロジェクトの公式ホームページは立ち上がっていませんが、バイオインダストリー協会が事務局を担当しています。本プロジェクトの内容は完全に秘密事項となっており、唯一、ユーザーフォーラムによって情報が収集できます。
 
 
 
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*本プロジェクトの謝辞を入れた論文を、以下に紹介します。
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論文一覧
 
2017
 
17. Itai S, Yamada S, Kaneko MK, Harada H, Kagawa Y, Konnai S, Kato Y*.
(*corresponding author)

Expression of cat podoplanin in feline squamous cell carcinomas.
Monoclon. Antib. Immunodiagn. Immunother., in press
 
16. Itai S, Yamada S, Kaneko MK, Chang YW, Harada, H, Kato Y*.
(*corresponding author)

Establishment of EMab-134, a sensitive and specific anti-epidermal growth factor receptor monoclonal antibody for detecting squamous cell carcinoma cells of the oral cavity.
Monoclon. Antib. Immunodiagn. Immunother., in press
 
15. Itai S, Fujii Y, Nakamura T, Chang YW, Yanaka M, Saidoh N, Handa S, Suzuki H, Harada H, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)

Establishment of CMab-43, a Sensitive and Specific Anti-CD133 Monoclonal Antibody, for Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., in press
 
14. Itai S, Kaneko MK, Fujii Y, Yamada S, Nakamura T, Yanaka M, Saidoh N, Handa S, Chang Yao-Wen, Suzuki H, Harada H, Kato Y.
(*corresponding author)


Development of EMab-51, a Sensitive and Specific Anti-EGFR Monoclonal Antibody in Western Blot and Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., in press
 
13. Itai S, Yamada S, Kaneko MK, Harada H, Kato Y.
(*corresponding author)


Immunohistochemical Analysis Using Anti-Podocalyxin Monoclonal Antibody PcMab-47 Demonstrates Podocalyxin Expression in Oral Squamous Cell Carcinoma Cells.

Monoclon. Antib. Immunodiagn. Immunother., https://doi.org/10.1089/mab.2017.0030
 
12. Yamada S, Itai S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Harada H, Kagawa Y, Ichii O, Konnai S, Kaneko MK, Kato Y.

PMab-52: Specific and Sensitive Monoclonal Antibody against Cat Podoplanin for Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., https://doi.org/10.1089/mab.2017.0027
 
11. Itai S, Fujii Y, Kaneko MK, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Takahashi M, Suzuki H, Harada H, Kato Y.

H2Mab-77 is a sensitive and specific anti-HER2 monoclonal antibody against breast cancer.

Monoclon. Antib. Immunodiagn. Immunother., 36(4): 143-148, 2017
 
10. Kaneko MK, Kunita A, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Ogasawara S, Ohishi T, Abe S, Itai S, Harada H, Kawada M, Nishioka Y, Fukayama M, Kato Y.*
Anti-Podocalyxin Antibody chPcMab-47 Exerts Antitumor Activity in Mouse Xenograft Models of Colorectal Adenocarcinomas.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 157-162, 2017
 
9. Yamada S, Honma R, Kaneko MK, Nakamura T, Yanaka M, Saidoh N, Takagi M, Konnai S, Kato Y.*
(*corresponding author)


Characterization of Anti-bovine Podoplanin Monoclonal Antibody PMab-44

Monoclon. Antib. Immunodiagn. Immunother., 36(3): 129-134, 2017
 
8. Kaneko MK, Nakamura T, Kunita A, Fukayama M, Abe S, Nishioka Y, Yamada S, Yanaka M, Saidoh N, Yoshida K, Fujii Y, Ogasawara S, Kato Y
(*corresponding author)


ChLpMab-23: Cancer-specific Human-Mouse Chimeric Anti-podoplanin Antibody Exhibits Antitumor Activity via Antibody-Dependent Cellular Cytotoxicity

Monoclon. Antib. Immunodiagn. Immunother., 36(3): 104-112, 2017
 
7. Ogasawara S, Kaneko MK, Yamada S, Honma R, Nakamura T, Saidoh N, Yanaka M, Yoshida K, Fujii Y, Kato Y.*
PcMab-47: Novel Anti-human Podocalyxin Monoclonal Antibody for Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., DOI: 36(2): 50-56, 2017
 
6. Yamada S, Ogasawara S, Kaneko MK, Kato Y.*
(*corresponding author)

LpMab-23: A Cancer-Specific Monoclonal Antibody against Human Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 36(2): 72-76, 2017
 
5. Yamada S, Kaneko MK, Nakamura T, Ichii O, Konnai S, Kato Y.*
(*corresponding author)

Development of mPMab-1, a Mouse-Rat Chimeric Antibody against Mouse Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 36(2): 77-79, 2017
 
4. Kaneko MK, Yamada S, Nakamura T, Abe S, Nishioka Y, Kunita A, Fukayama M, Fujii Y, Ogasawara S, Kato Y*
(*corresponding author)


Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity

Cancer Med., ,6(4): 768-777, 2017
 
3. Kaneko MK*, Abe S, Ogasawara S, Fujii Y, Yamada S, Murata T, Uchida H, Tahara H, Nishioka Y, Kato Y*.
(*corresponding author)


Chimeric Anti-human Podoplanin Antibody NZ-12 of Lambda Light Chain Exerts Higher Antibody-dependent Cellular Cytotoxicity and Complement-dependent Cytotoxicity Compared with NZ-8 of Kappa Light Chain

Monoclon. Antib. Immunodiagn. Immunother., 36(1): 25-29, 2017

2. Kato Y*, Kunita A, Fukayama M, Abe S, Nishioka Y, Uchida H, Tahara H, Yamada S, Yanaka M, Nakamura T, Saidoh N, Yoshida K, Fujii Y, Honma R, Takagi M, Ogasawara S, Murata T, Kaneko MK*
(*corresponding author)

Anti-Glycopeptide Mouse Monoclonal Antibody LpMab-21 Exerts Antitumor Activity Against Human Podoplanin via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity
Monoclon. Antib. Immunodiagn. Immunother., 36(1): 20-24, 2017
 
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2016
 
1. Ogasawara S, Honma R, Kaneko MK, Fujii Y, Kagawa Y, Konnai S, Kato Y*
(*corresponding author)

Podoplanin Expression in Canine Melanoma
Monoclon. Antib. Immunodiagn. Immunother., 35(6): 304-306, 2016


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