Gynecomastia ( Due to side effect of Prostate Cancer hormonal treatment)

A case of prostate cancer (post operative). He complainted breast pain and gynecomastia. He suffered sever pain. So we planed to treat his breast by radiation therapy with informed-concent.

Radiotherapeutic prophylaxis of estrogen-induced gynecomastia: a study of late sequela.

Int J Radiat Oncol Biol Phys. 1986 Mar;12(3):407-8.

Radiation therapy is an effective means of preventing the development of hormone-induced gynecomastia in men with cancer of the prostate. The efficacy and morbidity of this type of radiation was studied in a retrospective analysis of 87 patients referred for treatment from 1972 to 1982. Patients receiving DES as treatment for prostate carcinoma were treated with irradiation to the breast tissue. Patients were treated with 4 MV, 60Co superficial X rays. Doses range from 1200 to 1500 cGy in 3 fractions. The majority of patients had satisfactory results in terms of prevention of gynecomastia and mammalgia. There were few acute reactions noted and no evidence of long term sequela.

Several articles were found, I treat him by 4MV photon (15MV/3fr).

RtBreast 250, 250, 30degArc(Rt), 30degArc(Lt), 60,50

LtBreast 120, 140, 30degArc(Rt), 30degArc(Lt), 305,325

Each dose weight is 2.5Gy(/3Fr) , total dose 15Gy.

 last modification date: 2006/04/05